Joined in 2023 
82 
63 About this deal
In April 2023, he had a semen analysis which showed only 19% progressive, and these were “sluggish progression.” He had ZERO in “excellent progression.”
Everyone will have advice to give to you on how to get pregnant. ‘Have you tried…?’, ‘why don’t you just…?’ But ultimately, conception starts with the quality of the sperm and the egg. The best way to support your sperm (smallest cell in the body) and egg (largest cell in the body) is by creating a balanced metabolism at a cellular level – and this is exactly how Impryl ®works. The activated micronutrients in Impryl ® bring your body into a fine metabolic balance, allowing your body’s own natural antioxidant, glutathione, to optimise both egg and sperm quality as they develop. There aren’t many fertility supplements that provide this unique type of support. In fact, most fertility supplements provide unbalanced support: in other words, they focus on the benefit of one ingredient over others. Many contain strong antioxidants that can upset this important metabolic balance, damaging sperm and egg quality. But Imrpyl ®is different. Find out more about how Impryl ®can help you. Do you have PCOS? Impryl ingredients were carefully selected because each plays an important role in a process in your body called One Carbon Metabolism (OCM). OCM uses the micronutrients provided by Impryl to power five biological processes – homocysteine recycling, DNA/RNA synthesis, cellular energy production, natural antioxidant activity and gene expression – each important for sperm health and egg quality, fertilization, and the growth and development of the baby. What is One Carbon Metabolism (OCM)?
Q & A
Impryl, due to its content in methylfolate and methylcobalamine, that are able to enter the CNS, favors the decrease of glutamate by inducing its consumption for the synthesis of glutathione and by activating the removal of homocysteine within the CNS. Treated women reported a very fast relief from symptoms, already after 3 days of treatment, and almost all of them were symptom free after one week.
It is worth considering the following for your husband: standard sperm tests focus on quantity, motility and morphology but do not test for DNA fragmentation. Yes, Impryl can be used by individuals who consciously choose to avoid products of animal origin. In addition, none of the ingredients in Impryl are produced using genetically modified organisms (GMO). Does IMPRYL® contain any artificial colors or flavors? In addition, a per-protocol analysis will be performed for the primary outcome and the secondary outcomes overall pregnancy number, time to pregnancy, number of miscarriages and live birth rate. There is a great deal of clinical data showing that Impryl improves DNA fragmentation in the majority of patients, although sadly this was not the case for everyone.All couples will receive our standard care for infertility according to the guidelines of the Dutch Society of Obstetrics and Gynaecology. After diagnostic workup, couples will either start with EM (6 months), IUI, IVF or ICSI. Participants will take study supplement for a maximum of 6 months, even if the fertility intervention (6× IUI of 1× IVF/ICSI cycles) is not completed. There are many reasons why so many of us have difficulties with fertility. With 1 in 6 couples needing medical help to get pregnant and the causes of infertility being almost equally spread between men and women, it’s important to understand what factors can impact your fertility. Aside from any obvious medical health problems, lifestyle choices, environmental factors, diet and age can affect the chances of getting pregnant. For example, fertility in women starts to drop after reaching 35. This is because the age of the egg is a critical factor in achieving pregnancy. Women with PCOS often have difficulty ovulating and therefore have problems conceiving. Epidemiological studies have shown environmental factors have played a part in sperm counts dropping over the last 50 years and this trend continues. Even men with a ‘normal’ sperm count can have other problems such as DNA fragmentation, which can cause infertility and increase the incidence of miscarriage. Optimise your fertility Anyway, fast forward to August 2023. He has been taking Impryl for 4 months. He had a repeat analysis on Monday and I wasn’t expecting much. These were the results.
My wife and I had been trying for over a year before we considered there may be other factors affecting conception. We already have a child and had no previous issues conceiving so were surprised that it was taking longer than we had planned. DNA fragmentation is the ‘snipping up’ of DNA in the sperm head, which can contribute towards difficulties in conceiving and/or miscarriage. DNA fragmentation is often treated with strong anti-oxidants such as Vitamin C, Vitamin E, Selenium, CoQ10, Vitamin A and Carotenoids. However, we now know that although they might prevent DNA fragmentation, these strong anti-oxidants can then cause DNA de-condensation, which is the unravelling of the DNA in the sperm head, meaning that conception is not possible at all. Unlike Impryl, many other supplements contain these strong anti-oxidants. One tablet of Impryl should be taken each day with a full glass of water between meals. Ideally, Impryl should be taken at approximately the same time each day. How long should IMPRYL® be taken?The protocol and all protocol modifications are approved by the local METC at the Radboud University Medical Centre and by the national Central Committee on Research Involving Human Subjects with protocol ID NL61414.091.17.
Impryl is the benchmark of the antioxidants support. According to the new strategy, instead of using antioxidant substances, that act only on a limited number of sensitive pathways and that may generate negative counter effects, Impryl leverage on the physiologic antioxidant system to achieve a better oxy-redox balance within the control of the natural cellular homeostasis. This approach is resulting in clinical improvements that appeared impossible by using traditional antioxidant molecules. In addition Impryl contains only substances normally present in the diet for a easy and safe use with no limits of duration. He did cut down on caffeine a lot but probably actually drunk more and put on a bit of weight. I 100% think this is due to Impryl.Impryl contains riboflavin (Vitamin B2), niacin (Vitamin B3), pyridoxine (Vitamin B6), 5-methyltetrahydrofolate (activated Vitamin B9), methylcobalamin (activated Vitamin B12), zinc, betaine and L-cystine. These ingredients are either essential (must be consumed in the diet) or semi-essential (can be made in the body, but typically not in sufficient quantities) and several are in their activated forms (don’t require processing by the body). L-cystine is made of two cysteines and is the soluble and circulating form of cysteine. Into the cells, L-cystine is transformd into 2 cysteines on demand. Cysteine is the main substrate for the synthesis of the main physiologic antioxidants: glutathione (GSH) and of hydrogen sulfide (H 2S). What is the importance of Vitamin B2, B3 and B6? I wanted to post this because I felt devastated after the first analysis. Every single one of my husband’s parameters, including count, has improved drastically in % terms.
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