Protexin Veterinary Synbiotic D-C Daily probiotic and prebiotic capsules for dogs and cats (Pack of 1, 50 Capsules)

Product Information

Shreiner AB, Kao JY, Young VB. The gut microbiome in health and in disease. Curr Opin Gastroenterol 2015;31(1):69-75.

As with probiotics, the desired outcome after giving prebiotics is improvement of host health. 21 However, the specific aim of giving prebiotics is to promote growth and function of the beneficial bacteria already present in the gut. Intake of prebiotics can significantly modulate the colonic microbiota by increasing the number of specific bacteria and thus changing the composition of the microbiota. 23 Prebiotics are metabolized by the resident microbiota of the colon, which, depending on fermentability, will result in the production of the short-chain fatty acids butyrate, propionate, and acetate. 23 These metabolites will diffuse through gut enterocytes and provide either local effects (e.g., enhance the intestinal epithelial barrier, decrease pro-inflammatory cytokines, regulate intestinal motility) or systemic effects (e.g., provide energy for the host). 24,25 Apart from direct prebiotic effects, dietary fibers can have additional functions in the GI tract. Psyllium, for example, has water-binding and bile acid–binding properties that improve fecal consistency, increase the intestinal mucus layer, and have beneficial effects on cell proliferation in the intestinal tract. 26 Synbiotics TheEU-registered probioticEnterococcus faecium(DSM 10663/ NCIMB 10415) 4b1707, to help repopulate the intestine with beneficial micro-organisms. Probiotics are live microorganisms, prebiotics are nondigestible food ingredients that support resident intestinal bacteria, and synbiotics are a combination of both.D’Angelo S, Fracassi F, Bresciani F, et al. Effect of Saccharomyces boulardii in dog with chronic enteropathies: double-blinded, placebo-controlled study. Vet Rec 2018;182(9):258. Give one capsule daily by mouth or as advised by your veterinary surgeon.Capsules can be given whole or opened and the contents sprinkled onto food. Some resident bacteria that thrive on prebiotics might not have the same health benefits as exogenous probiotics. Administering probiotics and prebiotics together may enhance the potential for eliciting health benefits, and some commercially available products contain both probiotics and prebiotics. These combinations are called synbiotics. Safety and Quality Safety The most promising applications for probiotics are treatment of acute uncomplicated diarrhea, prevention of stress diarrhea, prevention of antibiotic-associated GI signs, and adjunct therapy for chronic enteropathies ( TABLE 1 ). Probiotics need 1 to 3 days to colonize the intestines. 19 When the goal is prevention of stress-related diarrhea (during periods of weaning, boarding, or traveling or for working dogs), prophylactic administration of a probiotic a few days to weeks ahead of the event may increase success. Similarly, if the goal is prevention of antibiotic-associated GI signs, administering probiotics a few days ahead of a procedure will increase success.

Give one capsule daily by mouth or as advised by your veterinary surgeon.Capsules can be given whole or opened and the contents sprinkled onto food. Specification Gibson GR, Roberfroid MB. Dietary modulation of the human colonic microbiota: introducing the concepts of prebiotics. J Nutr 1995;125(6):1401-1412. A prebiotic, consisting of fructo-oligosaccharide (FOS) and acacia (Gum arabic), to feed and stimulate the growth of beneficial bacteria. Bybee SN, Scorza AV, Lappin MR. Effect of the probiotic Enterococcus faecium SF68 on presence of diarrhea in cats and dogs housed in an animal shelter. J Vet Intern Med 2011;25(4):856-860.

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Suchodolski JS, Jergens AE. Recent advances and understanding of using probiotic-based interventions to restore homeostasis of the microbiome for the prevention/therapy of bacterial diseases.

Refrigerated items:when you purchace a cold chain product, you accept the rare chance that goods will not be delivered in an ideal condition and that no compensation will be offered to replaceSuchodolski JS. Diagnosis and interpretation of intestinal dysbiosis in dogs and cats. Vet J 2016;215:30-7.