Hand Chemistry Retin-Oil 100 ml

Product Information

Hydroxypinacolone Retinoate (HPR) is the newest member of the "royal family of skincare" ( see who is who onthis cool retinoids family tree), the retinoid family. The queen of the family is the FDA-approved anti-aging superstar, retinoic acid, aka tretinoin and HPR seems to be agentlebutinfluentialsister princessto the queen. For the same reasons they are popularly used, they are also commonly avoided. Anecdotally, many individuals have reported that Silicones cause/excerbate breakouts, irritation, cause a feeling of skin being unable to breathe, cause clumping of cosmetic products and find it difficult to wash off. As a result, those who find them problematic are avoiding them and increasingly, cosmetic companies are avoiding them as well. This has a slightly chemically scent, but there our niggles end. Apply morning and night to leave skin silky smooth, and to improve tone, redness and discolouration. We like to use it while on holiday to keep skin in good condition while tanning, and find it completely prevents peeling once you get home. The big promise ofHPR is that it's similarly active as retinoic acid (no conversion needed, remember) but without the irritation. According to the manufacturer's tests, 24 hours of an occlusive patch with 0.5% HPR resulted insignificantly lower irritation than 0.5% retinol. Also, there was a "dramatic reduction of lines and wrinkles" after applying 0.2% HPR around the eyes twice a day for 14 days.

It's a so-called retinoic acid ester,meaning that it's directly related to retinoic acid. If you've already read our description about retinol or retinyl palmitate, you know that the active ingredientour skin cells can interpret is retinoic acid. Other forms of retinoids have to beconverted by our metabolic machinery to do something. That's not the case with HPR. It binds directly to the retinoid receptors of the skin cellsto work its skincare magic. This iconic product is a luxurious multi-tasking dry oil (read: non-greasy) that works to repair skin AND hair. Lotions, on the other hand, are often better at penetrating skin because they're partly water-based. Parabens are a large group of preservatives which are used to prevent bacteria growing in cosmetic formulations.They help loosen up the dirt and grime from your skin and hair to allow for water to wash it away with ease.

Regarding anti-aging, there is a pretty recent, Estee Lauder sponsored study that compared the in-vitro (not on real human beings but on skin models) collagen-boosting effectiveness of Hydroxypinacolone Retinoate, tretinoin, good old retinol and retinyl palmitate(RP). The results are pretty encouraging showing that" HPR had greater levels of gene transcription than retinol and RP (RP) at the same concentrations ... however, HPR did not achieve gene transcription levels of ATRA (tretinoin)." But, a much higher dose might be tolerated from HPR and the highestdose of HPR out-performed tretinoin. Pretty encouraging, though we are very much waiting for a study to confirm all this on real human beings.However some sulfates are so good at their job, they can wash off your skin’s own natural oils that keep it moisturised and protected which can lead to dryness and irritation.