Healthspan Vein Vine 360mg (90 Tablets) | for Tired & Heavy Legs | Maintains Healthy Leg-Vein Functions | Red Vine Leaf Extract | Added Vitamins B1 & C | Vegan

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Although the red vine leaf extract studies were small in number, the available evidence suggests that AS 195 has properties that may help to maintain healthy leg-vein function. As such, its role in the prevention of CVI and in ameliorating established venous disease could be further explored. Such investigations may include evaluation of the correction of early vein changes to prevent venous ulceration and the role of red vine leaf extract in maintaining leg-vein integrity, thus leading to enhanced treatment options and a recurrence-prevention strategy.

Russian physicians recently added red vine leaf extracts to the immediate medical treatment of patients presenting with acute deep vein thrombosis (blood clots in a large vein in the lower leg). However, this doesn’t mean vine leaves aren’t healthy. There is ample research on the properties and health benefits of red vine leaves and several uses have been identified: Numerous studies report that the antioxidants in red vine leaves and the subsequent red vine leaf extract are efficient for the treatment of varicose veins, also known as chronic venous insufficiency. The extract has successfully been used in clinical trials to prevent edema (swelling) and other symptoms associated with the condition. Following a 42-day study, subjects reported an improvement in symptoms such as: tiredness and fatigue, pain, tingling and tension sensation in the legs ( Oedema protective properties of the red vine leaf extract AS 195 (Folia vitis viniferae) in the treatment of chronic venous insufficiency. A 6-week observational clinical trial). According to research, red vine leaves owe all of their health effect to their antioxidant content. Antioxidants found in red vine leaves include flavonoids (quercetin-3-O-beta-D-glucuronide, isoquercetin, myricetin, kaempferol), catechins, epicatechins, anthocyanins, procyanidins and proanthocyanidins. Other famous antioxidant compounds in the leaves include resveratrol, also found in grapes and grape wine, and viniferin, the main bioactive constituent in grapevine sap. ( Phytopharmacy: An evidence-based guide to herbal medicinal products).

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Red Vine Leaf Extract (AS 195) Can Improve Some Signs and Symptoms of Chronic Venous Insufficiency, a Systematic Review The effects of venous hypertension include deposition of haemosiderin (iron deposits) and fibrin in the perivessel tissues, along with subtle changes in skin texture that can eventually lead, if untreated, to trophic skin changes and varicose leg ulcers. Management of venous hypertension Antioxidants in general exhibit anti-inflammatory properties as well and can help reduce swelling and pain associated with inflammatory conditions. These biological active compounds also exert antimicrobial effects. A 2011 study from the International Journal of Food Properties revealed that red vine leaves hold strong antimicrobial properties against Staphylococcus aureus, Escherichia coli and Salmonella Infantis ( Phenolic Profile, Antioxidant Capacity, and Antimicrobial Activity of Leaf Extracts from Six Vitis vinifera L. Varieties). Red vine leaves have also been said to be heart friendly. By improving blood circulation in the body, the leaves decrease the chances of cardiovascular diseases. This product has been improved. At Healthspan we are constantly striving to provide products of the highest quality and sometimes that means we need to make changes to your supplements. Our new and improved Vein-Vine formulation now contains vitamins B1 and C, to support your heart health and blood vessels, while remaining at the same price as before. What is Vein−Vine?

One of the first studies to assess the effectiveness of red vine leaf extracts (Antistax) asked 71 people with leg swelling (due to chronic venous insufficiency) to take 360mg red vine leaf extracts, or placebo during two separate periods of 6 weeks. This meant that each person tried both treatments and acted as their own controls.

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The LipoTherapeia® treatment is exclusively provided at our practice in Marylebone, London (The Light Centre, Clearwater Court, 49 Marylebone High Street, London, W1U 5HJ) Recent studies have investigated the action of flavonoids in preventing atherosclerotic plaques (Hollman and Katan, 1997). Bioflavonoids or flavonoids are a class of water-soluble substances found in a number of plants or plant-derived products. It is believed that flavonoids have a wide range of beneficial effects when taken in the diet, including anti-inflammatory, antihistaminic and antiviral action. Formica and Regelson (1995) concluded that flavonoids are important in the maintenance of capillary wall integrity and resistance. Red Vine Leaf Extract has been used for ages by French farmers, and it was not until recently that the uses of this medicinal plant were discovered. It is an ideal ingredient in the treatment of Chronic Venomous Insufficiency, or CVI. CVI is a condition that affects the majority of the adult population. The extract contains a number of bioflavonoids including flavone/flavonol glycosides and glucuronides, in particular quercetin-3-O-b-D-glucuronide, isoquercitrin and kaempferol-3-glucoside. It is registered as an over-the-counter medicine in several European countries. What evidence is available for its use? As a result of this the person’s mobility is made easier as there is little to no pain, swelling, or stiffness in the legs.

In theory and at high doses, the red vine could reduce the action of classic anticoagulant or antiplatelet treatments. Physical mobilisation, avoidance of prolonged sitting or standing, and elevation of the legs reduce the venous pressure and facilitate venous return in the affected areas. Treatment centres around the application of external pressure to the limb to mechanically splint the vessels, preventing their distortion and engorgement by the physical narrowing of blood vessel lumen. In this way, faulty valves can be supported and intravessel blood velocity increased (Oduncu et al, 2004). Food supplements must not be used as a substitute for a varied and balanced diet and a healthy lifestyle. If you are pregnant, breastfeeding, taking any medications or under medical supervision, please consult a doctor or healthcare professional before use. Discontinue use and consult a doctor if adverse reactions occur. Not intended for use by persons under the age of 18. Keep out of reach of children. Do not use if seal under cap is broken or missing. Kalus, U. et al (2004) Improvement of cutaneous microcirculation and oxygen supply in patients with chronic venous insufficiency by orally administered red vine leaves AS 195: a randomised, double-blind, placebo-controlled, crossover study. Drugs and RD; 5: 2, 63-71.

This study showed a marked improvement in patients under treatment, both subjectively in terms of symptoms and objectively in limb measurements. Those receiving the higher-dose preparation experienced a slightly greater effect, and this was sustained for a longer period after the trial had been discontinued.